GLOBALEHR provides brilliant chance of readily retrieving the required information for conducting a faster and a much more accurate decision for action. Decline in medical errors is another important advantage of applying GLOBALEHR that should seriously be taken into account. Open source GLOBALEHRs have been designed to improve health-care while reducing the cost of similar proprietary systems. Those who developed OSS actually encourage it and rely on this philosophy to see the software spread and grow beyond its original creators. According to the findings, open source GLOBALEHR systems have been wildly welcomed by source limited regions around the world, especially in Sub-Saharan Africa and South America. Argentina, Australia, Chile, Ecuador, Ethiopia, Germany, Ghana, Haiti, Jordan, Kenya, Lesotho, Malawi, Malaysia, Mali, Mexico, Mozambique, Netherlands, Nigeria, Pakistan, Peru, Rwanda, Senegal, Sierra Leone, South Africa, Sweden, Tanzania, Thailand, Turkey, Uganda, USA and Zimbabwe are among countries, which used open source GLOBALEHRs to enhance the health care quality. The results indicated that many countries especially developing countries- demand to use an interoperable and cost-efficient GLOBALEHR system, which is flexible enough to modify and improve.